育世博生物科技股份有限公司

【About the role】 We have an exciting opportunity for motivated individuals to join our CMC team working to develop cell therapies against cancer. The successful candidate will be expected to be a good team player, work with enthusiasm to execute assignments properly. 【Position Title】 (Sr.) Research Associate 【Location】 Taipei, Taiwan 【Reports to】 Principal Scientist 【Job Type】 Full-time 【Responsibilities】 • Support IND enabling related study. • Optimize immune cell culture process. • Develop new projects generally on a yearly basis. • Manufacture cell therapy products in a GTP lab as a core team member. • Conduct QC tests to secure safety, stability, and efficacy for our valuable products. • Establish and maintain the documentation system. 【Qualification】 • Passionate about research, self-motivated, values teamwork, willing to join the international cell therapy drug development field. • Good communication and interpersonal skills. • Familiarity with flow cytometry-based experiments is a must. • Familiarity with tumor-killing assay experiments is a plus. • Familiarity with GTP Lab practice is a plus. 【Academic and/ or working experience】 • MSc (or above) in life science or related fields (pharmacology, immunology, chemistry, and biochemistry). • 2+ years of working experience with cell culture as the primary duty.

【About the role】 We're seeking an innovative and highly skilled Scientist to join our Antibody-Drug Conjugate (ADC) team. You'll play a pivotal role in the design, synthesis, and characterization of novel linker-payloads and the development of cutting-edge conjugation chemistry strategies. This position requires a strong foundation in Organic Chemistry, Bioconjugation Chemistry, Analytical Chemistry, Chemical Biology, structure-based drug design, and a deep understanding of drug mechanisms to evaluate and optimize payload performance. This highly collaborative role demands excellent communication skills to work effectively within a multidisciplinary team and contribute significantly to our ADC pipeline. 【Position Title】 Scientist, Antibody-Drug Conjugate (ADC) Chemistry 【Location】 Taipei, Taiwan. 【Reports to】 Associate Director of ADC Development 【Job Type】 Full-time 【Education /Background】 • Ph.D. in Organic Chemistry, Medicinal Chemistry, Chemical Biology, or a related discipline with a minimum of 3 years of relevant industry experience in biotech/pharmaceuticals, OR • M.S. with 7+ years or B.S. with 10+ years of highly relevant industry experience demonstrating exceptional expertise in ADC chemistry. 【Responsibilities include but are not limited to】 • Lead the design and synthesis of novel linker-payloads, focusing on optimizing stability, potency, selectivity, and pharmacokinetic properties for next-generation ADCs. • Apply advanced synthetic organic chemistry techniques to utilize structure-based drug design principles and computational chemistry tools to guide rational design. • Develop and optimize innovative conjugation methodologies for site-specific and heterogeneous antibody-drug conjugation. • Design and conduct experiments to evaluate the in vitro and in vivo performance of novel payloads and ADCs, correlating chemical structure with biological activity, and thoroughly assess payload mechanism of action. • Act as a subject matter expert in ADC chemistry, providing scientific guidance and contributing to project strategy. • Foster strong collaborative relationships with internal cross-functional teams, including protein engineering, biology, pharmacology, analytical chemistry, and CMC. 【Position Requirements & Experience】 • Extensive hands-on experience in multi-step organic synthesis, purification, and characterization (NMR, Mass Spectrometry, IR) of complex small molecules, with a deep understanding of reaction mechanisms, retrosynthesis, and protecting group chemistry. • Proven expertise in the design and synthesis of novel linker-payloads, specifically incorporating principles of medicinal chemistry (SAR, PK/PD optimization) and heterocyclic chemistry. • Strong experience with various bioconjugation techniques (e.g., maleimide, click chemistry) and a deep understanding of linker design strategies (e.g. site-specific vs. heterogeneous). • Proficiency in structure-based drug design principles and experience with relevant computational chemistry software (e.g., Schrödinger, MOE, QSAR modeling). • Solid understanding of drug mechanism of action for various cytotoxic agents (e.g., DNA damaging agents, tubulin inhibitors) and its implications for payload design and evaluation. • Strong background in analytical chemistry with extensive experience in interpreting data from characterization techniques essential for small molecules and ADCs (NMR, Mass Spectrometry, HPLC/UPLC, UV-Vis, and a familiarity with HIC, SEC, CE-SDS for ADCs). • Understanding of basic cellular and molecular biology relevant to drug action. • Excellent scientific writing, including publications, IND documents and presentations. • Excellent communication and interpersonal skills to foster collaboration across functions and with external partners. • Demonstrated ability to manage multiple projects simultaneously and deliver results within deadlines.

【About the role】 We are seeking a highly motivated and accomplished Associate Director to lead and advance our Antibody-Drug Conjugate (ADC) pipelines from preclinical research through IND-enabling studies. The successful candidate will possess a deep scientific understanding of ADC biology, chemistry, and linker-payload development/optimization, coupled with demonstrated leadership capabilities in managing scientific teams. This role requires an individual with exceptional communication and interpersonal skills to foster a collaborative internal environment and effectively manage external partnerships. The Associate Director will be instrumental in translating novel scientific discoveries into innovative ADC therapeutics, driving projects from the bench to IND submission. 【Position Title】 Associate Director, Antibody-Drug Conjugates (ADC) 【Location】 Taipei, Taiwan. (CA, USA) 【Reports to】 Sr. Director of R&D 【Job Type】 Full-time 【Education /Background】 • Ph.D. in life sciences (oncology, immunology, chemistry, medicine, or related field) with a minimum of 8 years of industry experience (at least 5 years of ADC experience) • BS/MS with at least 12 years of industry experience in ADC development. 【Responsibilities include but are not limited to】 • Provide scientific leadership and expertise in execution of ADC pipelines, including chemistry/bio-conjugation, antibody evaluation, linker-payload development, conjugation process development and preclinical study design. • Manage project timelines and resources to ensure alignment with corporate goals and timely delivery of milestones. • Prepare high-quality scientific documents, including peer-reviewed publications, regulatory submissions (e.g., IND), study reports, and slide decks for presentations. • Collaborate with internal teams, including clinical, regulatory, and manufacturing, to integrate ADC development efforts seamlessly. • Partner with external CROs for ADC manufacturing and scale-up processes. • Analyze and interpret experimental data, providing actionable insights to internal and external stakeholders. • Support due diligence and integration of external assets into Acepodia’s pipelines. • May supervise and mentor junior scientists and research associates. 【Position Requirements & Experience】 • Proven expertise in antibody selection/evaluation, linker/payload development, ADC pipeline development, including preclinical, pharmacokinetic, pharmacodynamic and toxicologic studies. • Hands-on experience in troubleshooting and resolving experimental challenges, with the ability to proactively identify issues, analyze root causes, and implement effective solutions. • Strong background in bioconjugation chemistry and analytical methods (e.g., LC-MS, HPLC, SEC). • Familiarity with CMC processes, including manufacturing and scale-up for biologics. • Excellent scientific writing, including publications, IND documents and presentations. • Excellent interpersonal skills with a proven ability to build strong relationships and foster collaboration across functions and with external partners. • A collaborative mindset and a strong team player. • Demonstrated ability to manage multiple projects simultaneously and deliver results within deadlines. • Strong verbal and written communication skills in English.

【工作內容】 • 根據 GMP 和 GDP 規則接收、儲存和運輸原材料 • 遵守財務要求完成採購流程 • 維護準確的庫存記錄 • 進行週期性盤點和實物盤點 • 依據訂單進行準備及包裝 • 操作倉庫設備，如清潔工具 • 保持倉庫環境的清潔與整潔 • 遵守所有安全程序和法規 【教育&工作經歷】 • 生物相關領域的學士學位或同等學歷 • 1-2 年在倉庫環境中工作的經驗，在製藥行業尤佳 • 對 GMP、GDP 的原則和實踐有深刻理解 • 能夠閱讀並理解安全程序，標準作業程序和法規 • 有能力實施安全要求並具有安全第一的意識 • 優秀的分析和解決問題的能力 • 優秀的溝通和人際交往能力 • 能夠獨立工作和團隊合作 • 瞭解採購流程，包括 PR/PO 和物料接收等流程 【其他條件】 • 夠獨立工作和團隊合作 • 能專注於細節和準確性 • 能夠舉起和搬動重物 • 能夠在快節奏和高要求的環境中工作 • 優秀的溝通和人際交往能力 • 有操作倉庫管理軟體和 Excel 的經驗 • 有參與品質控制作業流程的經驗 • 有遵從GMP、GDP 和法規要求的經驗 • 有參與採購作業的經驗

【About the role】 You will support the execution of Acepodia’s intellectual property (IP) operations by ensuring that all patent-related activities are strategically aligned with the company’s R&D roadmap and business objectives. In this role, you will work closely with the IP lead, R&D teams, and external patent counsel to translate scientific advancements into timely, high-quality IP actions. Your contribution will help strengthen the protection of Acepodia’s innovations and support the company’s long-term value creation. Your core responsibilities include organizing technical documentation throughout the patent prosecution process, monitoring competitors’ patent activities, and assisting with freedom-to-operate (FTO) analyses to support research and business strategies. You will also help facilitate communication between scientific teams and legal advisors, ensuring that our IP coverage evolves in parallel with R&D progress across both cell-based and non-cell-based pipelines. We seek a candidate with a background in chemistry, biology, or a related field, along with proven experience in patent prosecution or IP operations. The ideal candidate is detail-oriented, well-organized, and motivated to deepen their understanding of IP work in a dynamic biotech environment. 【Position Title】 (Senior) Patent engineer 【Location】 Taipei, Taiwan. 【Reports to】 Associate Director of Patent 【Job Type】 Full-time 【Education /Background】 • A Master's degree or above in biotechnology, pharmacology, chemistry, cell or molecular biology, bioengineering, or a related field, with a solid technical background in biotechnology, molecular biology, chemistry, biochemistry, and/or pharmacology. • Experience in patent or law firms with prior art searches, patent applications drafting, and legal or office action responses; and/or in biotech-related companies conducting freedom to operate (FTO) analyses. 【Responsibilities include but are not limited to】 • Support the implementation and execution of Acepodia’s patent portfolio management in alignment with the company’s R&D roadmap and business priorities. • Coordinate with R&D teams and external patent counsel to ensure timely and accurate handling of patent filings, responses, and other prosecution matters. • Assist in drafting technical descriptions and patent specifications, and support the preparation of response materials during prosecution. • Conduct internal patent searches and assist in freedom-to-operate (FTO) assessments, helping identify potential IP risks or opportunities. • Perform other IP-related assignments and responsibilities as delegated by the IP lead. 【Position Requirements & Relevant Skills & Experience】 • At least three years of experience in patent or law firms and/or in biotech-related companies. • MSc degree or above in biotechnology, pharmacology, chemistry, cell or molecular biology, bioengineering, biochemistry, or a related field. • Strong communication skills, both written and verbal. • Excellent analytical skills with strong attention to detail and problem-solving ability. • Must have proficiency in English.

【About the role】 We have an exciting opportunity for motivated individuals to join our CMC team working to develop cell therapies against cancer. The successful candidate will be expected to be a good team player, work with enthusiasm to execute assignments properly. This role is pivotal in translating our cutting-edge research into a robust and scalable manufacturing process, directly impacting our ability to deliver novel therapies to patients. 【Position Title】 Sr. Research Associate / Research Scientist (Process Development) 【Location】 Taipei, Taiwan 【Reports to】 Principal Scientist 【Job Type】 Full-time 【Responsibilities】 • Design and execute experiments for the development, optimization, and scale-up of immune cell manufacturing processes, including cell isolation, expansion, and cryopreservation. • Troubleshoot and resolve process challenges, utilizing a systematic approach (e.g., root cause analysis) to improve process robustness, yield, and consistency. • Evaluate and implement new technologies and equipment (e.g., closed-system bioreactors) to enhance process efficiency and product quality. • Perform cell manufacturing in a cleanroom environment under GTP/GMP guidelines, including meticulous execution of batch records and adherence to stringent aseptic techniques. • Perform in-process controls (IPCs) and product release testing, including cell count, viability, flow cytometry, and other characterization assays. • Author and revise technical documents, including standard operating procedures (SOPs), batch records, and development reports. • Establish the optimized manufacturing processes at the GMP manufacturing site. • Execute and document experiments to support the CMC (Chemistry, Manufacturing, and Controls) section for IND filings. 【Qualification】 • MSc (or above) in life science or related fields (e.g., Immunology, Cell Biology, Bioengineering, Biochemistry). • Minimum of 3 years of hands-on experience in mammalian cell culture with stringent aseptic techniques, preferably with primary human immune cells (e.g., T cells, NK cells). • Hands-on experience with multi-color flow cytometry for immunophenotyping. • Proven ability to work independently in experimental design, execution, and data analysis. • Excellent communication skills and ability to work collaboratively in a team-oriented environment. 【Preferred Qualifications】 • Experience in cell therapy process development, including the use of Design of Experiments (DoE) methodology. • Experience working in a GTP/GMP regulated environment. • Hands-on experience with closed-system cell processing platforms (e.g., CliniMACS, WAVE, bioreactors, cell processing system). • Experience with cell-based functional assays (e.g., cytotoxicity assays, cytokine release assays). • Experience in authoring technical documents such as SOPs or development reports. • Experience with cryopreservation development and optimization.